Microfluidic and photolithographic patterning

We are investigating novel methods to control cell-surface interaction through microfluidics and photolithographic localization of adhesive and non-adhesive (poly ethylene glycol) moieties on both known and novel materials

Glass surface modified with hydrophobic silane in rings causes beading of water droplets at regular intervals

Regional modification of patterned surface with PEO deters fibroblast adhesion for weeks in 10% serum

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Research Interests

1. BioMEMS
   Our efforts have focused on the development of microtechnology tools for cell biology research and tissue engineering applications.

2. Hepatic Tissue Engineering
   We study the effects of the tissue microenvironment on the hepatocyte phenotype in vitro, for applications in cell-based therapies.